IPF: time for the (ciliary) beat generation?

IPF: time for the (ciliary) beat generation?

Idiopathic pulmonary fibrosis (IPF), the most common of the idiopathic interstitial pneumonias remains a disabling, progressive lung disease with extremely poor prognosis, in which no pharmacological intervention significantly alters outcome. A relatively poor understanding of the complex pathophysiology of IPF continues to hinder the identification of effective therapies, and of patients most ...

Effect of Cilia Beat Frequency on Muco-ciliary Clearance

Background: The airway surface liquid (ASL), which is a ï‌‚uid layer coating the interior epithelial surface of the bronchi and bronchiolesis, plays an important defensive role against foreign particles and chemicals entering lungs.Objective: Numerical investigation has been employed to solve two-layer model consisting of mucus layer as a viscoelastic fluid and periciliary liquid layer as a New...

effect of cilia beat frequency on muco-ciliary clearance

background: the airway surface liquid (asl), which is a fluid layer coating the interior epithelial surface of the bronchi and bronchiolesis, plays an important defensive role against foreign particles and chemicals entering lungs. objective: numerical investigation has been employed to solve two-layer model consisting of mucus layer as a viscoelastic fluid and periciliary liquid layer as a newt...

Variability in ciliary beat frequency in bronchiectasis.

Ciliary beat frequency in transplanted lungs.

BACKGROUND Patients with lung transplantation are prone to respiratory infections. Generally this is attributable to the effects of immunosuppressive drugs but mucociliary clearance has been found to be impaired in these subjects. A study was performed to determine whether this finding is accompanied by a reduction in ciliary beat frequency (CBF). METHODS Six patients who had undergone single...